Definition of Hyperemesis gravidarum:
It is a severe type of vomiting of pregnancy which has got deleterious effect on the health of the mother and/or incapacitates her in day to day activities.
Incidence of Hyperemesis gravidarum:
1 in 1000 pregnancy.
Etiology of Hyperemesis gravidarum:
•Mostly limited to first trimester.
•More common in first pregnancy.
•Has got a familial history (Mother & sister)
•More common in unplanned pregnancy.
•More prevalent in molar pregnancy, multiple pg.
Theories of Hyperemesis gravidarum:
1)Hormonal – excess of hcG
3)Dietetic deficiency – Deficiency of vit B6, vit B1, protein.
4)Allergic or immunological basis.
5)Decreased gastric motility.